Jillian Jacqueline was born in Chester Springs, Pennsylvania, and spent most of her childhood there before moving to New York City in her early teens. A precocious talent inspired by the music playing on the family's stereo -- including Patsy Cline, Elvis Presley, the Dixie Chicks, Carole King, James Taylor, and Patty Loveless. At 9 years old, she became part of the cast of Christmas from the Heart, a Yuletide revue written by and starring the legendary Kenny Rogers that ran for three months on Broadway. She spent the next several years as part of Rogers’ touring show, and through Rogers she was introduced to country artists Billy Dean and Suzy Bogguss, who invited the young vocalist to join them on the duet single "Keep Mom and Dad in Love" in 2001, which debuted on the Top 50 Billboard Country Music Charts. After completing her studies at Philadelphia University in 2010, she relocated to Nashville and began making a name for herself as a singer and a songwriter. In 2013, Jacqueline cut six songs with songwriter and producer Richard Marx, and in 2014 Marx produced a single for her, "Overdue," featuring harmony vocals from Vince Gill. The tune became a major online success, racking up over a million streaming plays. Jacqueline followed "Overdue" with the Jillian Jacqueline EP in 2016. After signing with Big Loud Records in 2016, she released "Reasons," the lead radio single from her Side A EP which appeared later that year. For her August 2018 single, "If I Were You," Jacqueline collaborated with Keith Urban, returning a month later with a second single, "Sad Girls," which she co-wrote with Nashville songwriting hero Lori McKenna. These two songs were featured on Side B, the companion EP to 2017's Side A, which appeared at the end of 2018. During this time, she toured extensively with acts such as Thomas Rhett, Ryan Adams, Brett Eldredge, Devin Dawson, and Kip Moore, performed on Late Night with Seth Meyers, as well as a slot on Spotlight stage at O2 arena in London during C2C festival. 

By early 2019, Jacqueline and Big Loud parted ways, and Jacqueline independently released an anthem of hope during the pandemic, titled “Wait for the Light." After taking two years to write and record her first full-length album, Honestly, Jillian signed a distribution deal with Virgin Music and returned in 2022 with "Magic," a single co-written with Shane McAnally and her producer Tofer Brown. The 12 song album garnered Jacqueline a slew of critical acclaim (“Jillian Jacqueline is everything that is right in country music” -American Songwriter) and featured collaborations with TJ Osborne (of Brothers Osborne), Charlie Worsham, and the alt-pop duo Lucius.  She toured the album opening for CAM during her U.S. The Otherside tour, as well as for Kip Moore on a 9 date run in Europe. In 2024, Jacqueline has lent her songwriting prowess to writing for other artists, earning cuts on highly-anticipated debut albums from artists like Maggie Antone and Valley James, with more writing collaborations coming in 2025 under her deal with Kobalt publishing. After extending her deal with Virgin for a second album, Jacqueline began writing and recording what will undoubtedly her most personal album yet, slated to be released in the Fall of 2025.